Major advantages of XplainBio:

• Automation of all stages of interpretation of the results of NGS research
• Does not require knowledge of bioinformatics
• High specificity and sensitivity of the analysis
• High productivity
• Safety

Data interpretation principles inXplainBio:

1. The data processing results in determining:
• which parts of the genome were sequenced
• which mutations are found in these areas
• which of these mutations are pathogenic
  
  
2. It searches international databases of genetic variants and more than 80 different sources of information for most explicit description of genes and mutations.
3. Simultaneously, 3 algorithms for searching for germline and somatic mutations are used: GATK4, Strelka2 and DRAGEN. This can significantly reduce the number of false positive results
4. The XplainBio system is constantly updated, now there are about 8,000 BRCA1 / 2 gene mutations in the database

Features of XplainBio

• High productivity - up to 300 exomes per day
• The system can process any gene panels
• The data is provided in an easy-to-understand report that is generated automatically and can be customized
• Parallel processing of samples is possible
• Search for known mutations is carried out automatically
• Found mutations are evaluated for reliability and pathogenicity
• Support module helps physicians make informed decisions
• Users can develop and download a database of classified and registered variants